RNA-Binding Protein EWS

A ubiquitous hnRNP protein that contains an RNA RECOGNITION MOTIF and C-terminal ranBP2-type zinc finger. It localizes to the CELL NUCLEUS and CYTOPLASM and is expressed as different isoforms in various tissues, interacting with CALMODULIN and TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Translocations that result in the formation of fusion proteins containing parts of RNA-binding protein EWS are associated with EWING SARCOMA.

Also Known As:

EWS Protein; EWS Proto-Oncogene Protein; EWS RNA Binding Protein 1; EWSR1 Protein; Ewing Sarcoma Breakpoint Region 1 Protein; Ewing Sarcoma Breakpointregion 1 Protein; EWS Proto Oncogene Protein; EWS, RNA-Binding Protein; Protein, EWSR1; Proto-Oncogene Protein, EWS; RNA Binding Protein EWS

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - RNA-Binding Proteins: 3262
      - Ribonucleoproteins: 1286
        Heterogeneous-Nuclear Ribonucleoproteins: 446
        RNA-Binding Protein EWS: 61
      - RNA Recognition Motif Proteins
        Heterogeneous-Nuclear Ribonucleoproteins: 446
        RNA-Binding Protein EWS: 61
    - Calmodulin-Binding Proteins: 398
      - RNA-Binding Protein EWS: 61
  - Nucleoproteins: 1870
    - RNA-Binding Proteins: 3262
      - Ribonucleoproteins: 1286
        Heterogeneous-Nuclear Ribonucleoproteins: 446
        RNA-Binding Protein EWS: 61
      - RNA Recognition Motif Proteins
        Heterogeneous-Nuclear Ribonucleoproteins: 446
        RNA-Binding Protein EWS: 61
  - Intracellular Signaling Peptides and Proteins: 32
    - RNA-Binding Protein EWS: 61
  - Neoplasm Proteins: 2
    - Oncogene Proteins: 7793
      - Proto-Oncogene Proteins: 7
        RNA-Binding Protein EWS: 61
- Peptides: 82426
  - Intracellular Signaling Peptides and Proteins: 32
    - RNA-Binding Protein EWS: 61

C Hattinger Selected Research

C Hattinger Research Topics

Disease

Drug/Important Bio-Agent (IBA)